Add variables to tuple

I am creating a database connection.While trying to add to the DB, I am thinking of creating tuples out of information and then add them to the DB.

I am taking information from the user and store it in variables.Can I add these variables into a tuple? Can you please help me with the syntax?

I only need the tuple to enter info into the DB. Once the information is added to the DB, should I delete the tuple? I mean I don't need the tuple anymore.