Tuples are immutable; you can't change which variables they contain after construction. However, you can concatenate or slice them to form new tuples:
a = (1, 2, 3)b = a + (4, 5, 6) # (1, 2, 3, 4, 5, 6)c = b[1:] # (2, 3, 4, 5, 6)
And, of course, build them from existing values:
name = "Joe"age = 40location = "New York"joe = (name, age, location)